About 15000 Sft facility located in the 1st & 2nd Floors of R&D Building, Ramky Commercial Hub, J.N. Pharmacity, Vishakhapatnam, Andhra Pradesh. Clavita R&D center is the hub of focused scientific activity with a team of about 40 scientists with Masters and PhD degrees.
The main research areas are APIs and Nutraceuticals development including cost effective technologies scalable to commercial level, innovative synthetic routes and environment friendly commercial processes. The Labs are recognized by DSIR.
1. R&D strategy:
- Identifying and developing key technologies suitable for producing the intermediates and APIs in cost-effective manner.
- Developing expertise in special techniques like Photochemistry at commercial level for producing challenging APIs
- Exploring the possibilities of telescopic processes to simplify the overall synthetic routes
- Obtaining the products in high enantiomeric purities
- Producing the pure polymorphs or crystalline forms
- Conforming the new processes developed to all IP and other regulations
2. Chemical development
- A team of 30 process research scientists and 31 fume hoods in 2 spacious laboratories
a. Flow of process development:
- Synthetic Routes evaluation
- IP assessment
- Exploring the possibility of new technologies development
- Process development and optimization
- Technology transfer and Scale up
b. Chemistry capabilities
- Alkylations and Acylations
- Carbonylations
- Catalylic reductions &Hydrogenations
- Grignard reactions
- Low temperature reactions
- Moistures sensitive reactions
- Organometallic reactions
- Stereo Selective and Chiral Resolutions
- Suzuki Coupling and Sonagashira Coupling
- Wittig Reactions
- Photochemistry
- Resin based purifications
3. Analytical development capabilities
a. A team of 10 analytical scientists with extensive method development and validation experience
b. Key instruments including:
- HPLC systems (analytical and preparative)
- GC systems
- UV spectrometer
- FTIR
- Polarimeter
- Stability chambers
c. Analytical capabilities
- Method development and optimization)
- Method validations
- Standards qualification
- Impurities qualification